University of Health and Rehabilitation Sciences School of Life Sciences and Health
Research Interests
Blood-Brain Barrier dysfunction mechanisms
Neurovascular homeostasis and neurodegenerative diseases (e.g., Parkinson's disease)
Cardiopulmonary rehabilitation and cardiovascular health
Intersection of neurobiology and rehabilitation medicine
Protective effects of exercise rehabilitation on BBB and molecular mechanisms
Endothelial cell energy metabolism in BBB homeostasis
Aging and inflammation-related BBB damage
Professional Affiliations
- Youth Committee Member, Cardiovascular Pharmacology Committee, Chinese Pharmacological Society
Academic Honors
- Shandong Taishan Scholar Young Expert
- Distinguished Level Funding from Peking-Tsinghua Joint Center for Life Sciences Postdoctoral Fund
- High-level Introduced Talent
Professional Experience
Ph.D. in Neurobiology, Peking University Health Science Center
Ph.D. in Neurobiology, Peking University Health Science Center
Joint Postdoctoral Training, Peking University - University of Health and Rehabilitation Sciences / Shandong University
Joint Postdoctoral Training, Peking University - University of Health and Rehabilitation Sciences / Shandong University
Biography
Zhan Rui, Research Professor and Associate Professor at the School of Life Sciences and Health, University of Health and Rehabilitation Sciences. Ph.D. in Neurobiology from Peking University. Joint postdoctoral training at Peking University - UHRS/Shandong University, joining Academician Dong Erdan's Cardiovascular Health Promotion Team. Principal Investigator of the Neurovascular Homeostasis and Blood-Brain Barrier Function Rehabilitation Team at UHRS.
Awards & Recognition
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Publications & Representative Works
Complete Bibliography
2023
NAD+ rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis, Neuron, 2023
NAD+ rescues aging-induced blood-brain barrier damage via the CX43-PARP1 axis, Neuron, 2023
2022
Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy, Nature Communications, 2022
Gut microbiota production of trimethyl-5-aminovaleric acid reduces fatty acid oxidation and accelerates cardiac hypertrophy, Nature Communications, 2022
2022
Effect of Lipoprotein(a) on Stroke Recurrence Attenuates at Low LDL-C and Inflammation Levels, Stroke, 2022
Effect of Lipoprotein(a) on Stroke Recurrence Attenuates at Low LDL-C and Inflammation Levels, Stroke, 2022
2021
Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection, European Heart Journal, 2021
Untargeted metabolomics identifies succinate as a biomarker and therapeutic target in aortic aneurysm and dissection, European Heart Journal, 2021
2018
Dapsone protects brain microvascular integrity from high-fat diet induced LDL oxidation, Cell Death & Disease, 2018
Dapsone protects brain microvascular integrity from high-fat diet induced LDL oxidation, Cell Death & Disease, 2018
